Environmental

Environmental Management Statement

Enanta is committed to safe working conditions and environmentally responsible practices. Enanta is also committed to being fully OSHA compliant and to complying with all federal, state and local environmental and safety laws and regulations.

The Company is proud to have a longstanding record of compliance with city, county, state, and federal environmental laws and permits, including the following:

Airborne Emissions

Waterborne Effluents

External Radiation Levels

Indoor and Outdoor Noise

Solid and Bulk Waste Disposal Practices

Handling and Storage of Toxic and Hazardous Materials

We seek to maintain a positive and proactive attitude towards best practice in these aspects of Enanta’s operations.

Environmental, Health and Safety

Policy

Enanta has developed and implemented a proactive Environmental, Health & Safety (EHS) Program designed to assist employees in performing their job tasks in a safe manner while complying with all pertinent federal, state, and local regulations.

The EHS Program includes necessary precautions to protect employees, the facilities, and the environment from hazards associated with our industry. The comprehensive EHS Program is detailed in our Health and Safety Manuals: The Emergency Action Plan, Biosafety Manual, Bloodborne Pathogens Plan, Chemical Hygiene Plan, Radiation Safety Plan, Respiratory Protection Program, DOT Security Plan, and Hazardous Waste Contingency Plan. Electronic copies of these manuals may be found on the Company Intranet in the Safety Section for all employees to view. OSHA documents are posted throughout our organization to be visible to employees.

Workplace Safety

Safety is the responsibility of each individual at Enanta.

All employees are responsible for maintaining a safe working environment. This includes all employees, supervisors and Environmental Health and Safety personnel. All work activities are to be conducted in a safe manner, reporting all work-related incidents and accidents, monitoring work areas for safety/housekeeping issues, and taking the appropriate steps to eliminate hazards from the work environment.

Enanta has specific requirements related to aspects of the work environment, including health and safety, and it expects all Enanta employees and visitors to comply with them. While not a comprehensive list, a few examples of such guidelines include:

Personal Protective Equipment

Emergency Procedures

Medical Emergencies

Chemical Hygiene

Biological Safety

Radiation Safety

Hazardous Waste Management

Hazard Communication

Facilities

Security (Including Visitors)

OSHA Guidelines

Incident DART Rates

We are proud of our exceptional safety record, which has resulted in zero claims for workers compensation during 2020 and 2021.

Environmental Footprint

Enanta Pharmaceuticals, Inc. does not own any real property. It leases portions of two buildings in Watertown, MA that have other tenants, and the utilities other than gas heat at one location are provided by the landlord, with Enanta paying for its share. These two leased premises comprise the entirety of the Company’s real estate footprint. The information below is based on good faith estimates supplied by the owner of these buildings – the life science specialty realtor Alexandria Real Estate (ARE) and its affiliates.

Energy Consumption

1. Enanta’s electricity usage consists of electricity provided by ARE, which means that ARE owns credit for the renewable sources. Enanta’s allocation of the usage of the building’s electricity is based on the square footage of Enanta’s leased space in each building as a percentage of the total rentable space in the building. During 2020, ARE had to enter into new contracts for electric service for each of the buildings (including one that had been recently acquired), resulting in a change in its mix of renewable and non-renewable sources. The mix of sources shown here is based on the mix reported by ARE as the purchaser of the power.

2. Natural gas usage estimates for the leased office building are provided by ARE based on the square footage of Enanta’s leased space as a percentage of the total rentable space in the building; natural gas usage for the leased laboratory building is derived directly from invoices issued to Enanta by the gas utility.

3. Up to a maximum of 110L of oil consumed annually; average oil consumption estimated at approximately 77L annually.
4. Based on 110 Liters diesel delivered for emergency generator use. No diesel consumed in 2020.

5. Based on the square footage of Enanta’s leased space in each building as a percentage of the total rentable space in the building.

Waste

6. Based on the square footage of Enanta’s leased space in each building as a percentage of the total rentable space in the building.

7. For laboratory facility only; office facility does not produce hazardous waste.
8. Enanta contracts with a third-party company that collects all hazardous (excepting biohazardous) waste. The waste mainly consists of flammable solvents, contaminated lab debris, and expired reagents. The solvents are sent to a facility in Canada where expired reagents are mixed with other expired waste solvents and sent for energy recovery as fuel for cement kilns around Canada. As the waste collected from Enanta is exported, the Environmental Protection Agency (EPA) technically classifies it as “transferred” vs. “sent for energy recovery.”

Emissions

Fumes and vapors from all experiments are discharged through vents that are separate from any building HVAC system. With respect to ASHRAE 110 requirements, no significant off-gassing takes place in Enanta-occupied labs or facilities. The low volume of output is below the threshold at which EPA requires filters or scrubbers to be used. Therefore, emissions with respect to ASHRAE 110 requirement are not material to Enanta for the reasons cited.

Training and Compliance

At Enanta, we have numerous separate training modules related to safety practices, environmental management, and compliance with regulations. Many of these training modules are required to be completed during new hire safety trainings. Employees are given applicable trainings based on their roles and their job locations in our buildings. Examples of mandatory training modules include:

Biological Safety & Biological Safety Manual

Bloodborne Pathogens Training & Bloodborne Pathogens Plan

Chemical Hygiene Training & Chemical Hygiene Plan

COVID Onsite Work Protocol

Cyber Security Incidence Response Plan

Emergency Procedures Training & Emergency Actions Plans

Hazard Communication

Personal Protective Equipment

Radioactive Materials Awareness

RCRA Hazardous Waste

Respiratory Protection

Security Policy

Sharps Safety

Additional trainings are provided by employees’ direct supervisors and conducted through outside third-party experts. These can include DOT HAZMAT, OSHA, and IATA training modules, to name a few. At Enanta, we track our compliance with mandated safety courses and have full compliance with these safety training requirements.